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Free in vivo testing: Unleash your molecule's potential as a crop protector
  • Background
  • What we're looking for
  • What we can offer you
  • Who we are
  • Q&A
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Get them answered by the team at BASF.
Background

You’ve already done all the hard work of synthesizing your molecule. Maybe it wasn’t the blockbuster pharmaceutical you envisioned, but it still has potential!  

 

Now, we would like to partner to bring new life and impact from your chemistry. You may submit multiple compounds, and we will screen them using our computer models. If they are selected, you will receive the biological results for each compound as a potential herbicide, fungicide and insecticide, and you are free to publish the results. 

 

If there is a hit, it’s up to you to decide about follow up collaboration.  

 

Start the collaboration with us: let’s discover together if that next crop protection blockbuster is sitting in your deep freezer! 

 

Process 
  1. Submit proposal on Halo  

  2. Sign MTA agreement through DocuSign 

  3. Upload file with structures to BASF's platform 

  4. In silico evaluation & BASF decision 

  5. In vivo test of selected compound at BASF 

  6. Return of in vivo results for publication  

  7. Further collaboration

What we're looking for

We are looking for novel compounds, such as organic molecules, natural products, and fragment-like molecules, which could be subjected to screening within our research facility, with the goal of developing new crop protection products.

Solutions of interest include:
  • Small organic molecules
  • Natural products
  • Virtual compounds
  • Single chemical compounds (in a dry form)
Our must-have requirements are:
  • The minimum amount of compound we will accept is 5 mg (the standard amount is 8 mg).
  • The material shall have purity greater than 80% as determined by current state-of-the-art analysis.
Our nice-to-have's are:
  • Additional amounts of compound available for further screenings (20-100 mg) if needed.
  • Analogues compounds of submitted molecule if the parent compound turns out to be a hit in the initial screening.
What's out of scope:
  • Extracts or mixtures of compounds
  • Solutions in solvents
  • Metal-containing molecules
  • Polymers
  • Nanoparticles
  • Microorganisms
  • Toxic or explosive compounds
What we can offer you
Benefits:
Expertise
Partner receive logistic support and guidance over each step of the collaboration. Possibility to develop further collaboration with BASF researchers, based on preliminary results.
Facilities and Services
Free shipping of participant's compounds to BASF. To ensure the best solution and simple procedures, we also provide you free of charge our packaging materials (vials/tubes and boxes).
Compounds and Reagents
Synthesis cost for the re-ordered compound for further in vivo tests could be reimbursed.
Data
Biological results from the preliminary tests.
Who we are

As a global chemical company, we operate in diverse markets with varying requirements. To ensure responsible conduct and maintain our license to operate, we are guided by our core values and standards. These values shape our daily actions and foster respectful relationships with colleagues, customers, and partners.

Our teams are committed to putting health and safety first, making sustainability a part of every decision, and meeting strict compliance and environmental standards. We embrace diversity—in people, perspectives, and experiences—and promote open feedback grounded in honesty, respect, and trust. We see setbacks as opportunities to learn and improve.

 Learn more
Reviewers
Q&A with BASF

The Q&A is now closed.

Sort by:
Q.
Hello, we have some potential fungicides and a new biocide molecule ready to test. How much quantity do you need for your testing platform?
2
A.
Dear Gabriele, We need min 5mg to be able to test your compounds in our in vivo assays (as fungicide, herbicide and insecticide). best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 13, 2026
Is this response helpful?
0
0
Q.
We have created and are producing a super-pharmaceutical nanodrug with unlimited potential.These are nanoparticles.This is a strategic technology for the chemical industry.
1
A.
Dear Mykhailo, Thank you for contacting us, but unfortunately nanoparticles are out of scope for this program. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
September 17, 2025
Is this response helpful?
0
0
Q.
Will the submitted compound structures remain confidential within BASF?
JG
Jessy Mc Gowan, , Colorado State University
December 1, 2025
1
A.
yes, they will remain confidential. Hits from in silico screening will be visible for BASF coworkers. Summited to in silico but not selected compounds will be known only to gate-keeper.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
December 11, 2025
Is this response helpful?
0
0
Q.
Dear BASF, I teach post graduate students to design novel compounds for our targets. Please describe your targets are for "In silico evaluation & BASF decision " and we can design a new compounds for you.
1
A.
Dear Zeno, Thank you very much for your offer to design novel compound, but it is out of the scope of this project. We are interested in screening of compound libraries that already exist or could be provided after in silico filtering step. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 10, 2025
Is this response helpful?
0
0
Q.
Lancer, produced by Treibacher, is largely cerium citrate, and is a growth promoter for pigs and chickens (to replace antibiotics), and is also used in China for crop promotion. Has it been tested for crop protection?
1
A.
I do not think so
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
December 11, 2025
Is this response helpful?
0
0
Q.
Would 80+% pure plant extract (isolated molecule) be in scope? What information we need to share before submitting our product and can you share what was already tested, so we don't offer molecules you have
1
A.
Dear Ihor, yes, 80% pure plant extract will be in scope of the program. Once you submit the structures of your compounds to our platform, we will proceed with the in silico screening and inform you about the results. In this step we deselect known to us compounds, so we minimize the cross contamination risk. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
December 18, 2025
Is this response helpful?
0
0
Q.
Are small proteins / peptides within the scope? We have a recombinantly produced and purified candidate with in vitro validated anti-fungal activity at nanomolar to low micromolar range.
1
A.
yes, please submit your proposal :)
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 13, 2026
Is this response helpful?
0
0
Q.
Hello We have synthetic small molecule with antifungal properties. Which pathogens are you targeting?
1
A.
please contact me at <oipAgro@basf.com>. thank you.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 20, 2025
Is this response helpful?
0
0
Q.
Hello would we be able to submit a proposal with only smiles strings for the structures?
1
A.
yes, please submit your proposal.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 13, 2026
Is this response helpful?
0
0
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