- Background
- What we're looking for
- What we can offer you
- Q&A
The hair, skin, and nails supplement market has grown rapidly, but many products remain centered on familiar inputs such as vitamins, minerals, collagen, biotin, and general antioxidants. While some ingredients have evidence supporting benefits for skin hydration, elasticity, hair quality, or nail strength, the category often lacks strong scientific differentiation tied to the biological drivers of aging.
Aging affects hair, skin, and nails through interconnected systemic and tissue-level processes, including changes in cellular energy metabolism, inflammation, oxidative stress resilience, extracellular matrix integrity, nutrient sensing, microbiome balance, and regenerative capacity. These mechanisms overlap with recognized hallmarks of aging and may influence visible outcomes such as hair density and quality, skin elasticity and radiance, and nail strength over time.
Recent advances in longevity science, microbiome research, bioactive peptides, mitochondrial health, NAD+ biology, autophagy, senescence modulation, and nutraceutical delivery have created new opportunities to develop ingestible beauty solutions with stronger mechanistic rationale. Ingredients that modulate biological aging pathways associated with hair, skin, and nail health may enable differentiated beauty-from-within products and support claims around hair longevity, skin elasticity and glow, and nail strength.
We are looking for ingestible ingredients, ingredient platforms, or finished-format technologies (powders, capsules, gummies, soft chews, beverages, sachets, patches, other) designed to modulate one or more of the 12 hallmarks of aging relevant to hair, skin, and/or nail biology. Ideal solutions would demonstrate potential to support measurable beauty-related benefits.
- NAD+ precursors relevant to hair, skin, or nail health
- Senolytic/senomorphic ingestibles
- Mitophagy- and mitochondrial-supporting actives
- Biodesigned vegan collagen peptides
- Novel, bioavailable hair/skin/nail-targeted actives
- Postbiotic, probiotic, or psychobiotic platforms for cosmetic applications
- Adaptogens or botanicals linked to aging-related pathways
- Mechanism rationale connected to one or more of the 12 hallmarks of aging, supported by preliminary scientific evidence, peer-reviewed evidence in human-relevant models, or clinical studies
- GRAS, NDI-eligible, established history of safe use at proposed dose (US DSHEA pathway) or other plausible regulatory pathway for use in ingestible products (e.g., NHP Canada, EU food supplement, Novel Food, or similar frameworks where applicable)
- Bioavailability or pharmacokinetic data supporting absorption at cosmetically relevant doses
- Clear articulation on why the solution is newer, better, or different from existing approaches
- Stability data in a finished format (capsule, sachet, gummy, or powder) over 18-month shelf life at 25°C/60% RH
- Published or in-progress randomized controlled human trial with hair, skin, or nail endpoints
- Ingredient-level traceability and sustainable sourcing (precision fermentation, regenerative agriculture)
- Vegan, allergen-free, or clean-label profile
- Synergistic data when combined with topical longevity actives
- Topical-only ingredients
- Drug-development compounds requiring Investigational New Drug (IND) or New Drug Application (NDA) approval pathways
- Generic biotin or commodity multivitamin reformulations
- Ingredients lacking credible safety or efficacy data
The Q&A is now closed.
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