- Background
- What we're looking for
- What we can offer you
- Q&A
Individuals on glucagon-like peptide-1 (GLP-1)–based weight-management medications may eat substantially less, making it harder to maintain adequate energy, protein, micronutrient and fluid intake. Smaller portions and fewer eating occasions can make balanced nutrition difficult, particularly when dietary guidance is limited, and may be accompanied by fatigue, sluggishness, sleepiness, feeling cold or drained, and reduced physical functioning.
Adequate protein is important for preserving lean mass during weight loss, but protein alone does not ensure overall nutritional adequacy. Users may still consume too little energy or fall short on carbohydrates, fats, vitamins, minerals or fluids. Supporting them therefore requires a broader nutritional approach that makes an appropriate balance achievable within smaller quantities they can comfortably consume.
Research has highlighted the importance of protein and micronutrient management in this population, while energy expenditure, thermogenesis, glucose homeostasis and mitochondrial function remain areas for further investigation. Together, these findings point to an opportunity to develop nutrient-dense solutions that deliver meaningful nutrition in small servings while supporting sustained physical energy. Taste, texture and gastrointestinal tolerability will be critical to making these solutions practical and easy to consume consistently.
We are looking for solutions that help sustain everyday physical energy during reduced intake by improving nutritional adequacy, protein-energy delivery, hydration, nutrient utilization, or cellular/metabolic energy, without relying primarily on stimulants. We welcome ingredients, bioactives, novel combinations, delivery/formulation solutions, and food-matrix technologies.
Ingestible solutions should suit compact formats such as concentrated, clear, dairy- or plant-based beverages and shots; gels, jellies, spoonable or other semi-solid products; savory formats; snacks, bars or chews; powders or sachets; frozen or structured foods; hybrid food-supplement formats; or other formats offering a clear advantage for consumers with reduced appetite.
The ultimate goal is to develop solutions that deliver the highest practical nutritional and functional value in the smallest acceptable volume without compromising consumer enjoyment.
- Processes and technologies enabling high nutritional density in small portions
- Compact, high-quality protein and protein-fiber systems
- Protein systems with improved digestibility, amino-acid quality, tolerance, or sensory performance
- Slow-release carbohydrate and sustained-delivery systems
- Technologies supporting cellular energy production, mitochondrial function, or metabolic flexibility
- Nutrients, cofactors, peptides, metabolites, or bioactives supporting energy metabolism
- Hydration and electrolyte systems designed for consumers with reduced intake
- Technologies supporting thermoregulation during low caloric intake
- Biotics and microbiome technologies
- Nutrient absorption and food-matrix delivery technologies, e.g., encapsulation, emulsion, complexation, bioavailability or delivery systems
- Integrated systems combining protein, fiber, micronutrients, hydration, and energy support
- Flavor and sensory technologies enabling unusually high nutrient density
- Clear differentiation and intended sustained-energy outcome(s): reduced fatigue; stable physical energy; improved protein-energy adequacy, hydration, micronutrient status, lean mass, or cellular-energy outcomes; high-density nutrition in a small, well-tolerated serving; avoidance of energy spikes and crashes
- Scientific basis appropriate to maturity: early concepts need a scientific rationale and testable hypothesis; defined mechanisms need in vitro, preclinical, and/or human data where available, with GLP-1 relevance noted
- Reasonable basis to expect safe ingestion or current regulatory status and available safety data for market-ready solutions
- Human evidence, especially in GLP-1 users, intentional weight loss or calorie restriction, or other relevant at-risk populations
- Delivers multiple complementary benefits, e.g., sustained energy plus protein, fiber, hydration, micronutrients, bone or muscle support
- High nutritional and functional value in a compact format without compromising taste, texture, GI tolerance, stability, or enjoyment
- Complements protein and fiber foundations
- Reduces the number of products, pills, or eating occasions required
- Works across multiple food or beverage formats, where relevant
- Provides a clear, credible consumer-facing benefit
- Protected by defensible IP or otherwise difficult to replicate
- Manufacturing or deployment readiness, with a credible path to scale at a commercially realistic cost
- Conventional energy drinks or technologies relying primarily on caffeine, nootropics, or other stimulant effects
- Standard supplements without meaningful differentiation, proprietary science, or a novel delivery advantage
- Solutions whose anticipated effective dose would require impractically large servings, or that lack a credible path to acceptable sensory quality, GI tolerance, stability, and compact-format delivery
- Solutions focused primarily on appetite suppression, satiety, or sports performance rather than everyday sustained energy and functioning
- Conventional meal replacements that do not address the need for meaningful nutrition in small-volume servings
- New pharmaceutical GLP-1 agonists or other weight-loss drugs, and solutions intended to replace medical care
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