Bio-based encapsulation technology for hydrophobic liquid actives

Technology
In development
Company

Nanostructured lipid carriers for efficient encapsulation of hydrophobic active ingredients, enhancing stability and minimizing release in aqueous environments, suitable for agrochemical and cosmetic applications.

Overview

This bio-based encapsulation technology focuses on creating nanostructured lipid carriers to encapsulate hydrophobic liquid active ingredients. By leveraging a micrometer-sized melt emulsion process, this technology forms stable particles that confine hydrophobic cores, thereby enhancing the stability of active ingredients in aqueous environments. This solution is designed to maximize active ingredient loading while minimizing release, making it particularly valuable for agrochemical and cosmetic applications.

Technical specifications

The technology employs scalable processes utilizing industrial emulsifiers, high shear rates, and rapid cooling to produce defined particles. Key features include:

  • Encapsulation efficiency of 98-99%
  • Ability to encapsulate up to 30% active ingredients
  • Use of biodegradable surfactants and natural resins for particle stability
  • Adjustable particle tightness and dimensions through manipulation of viscosity and emulsification parameters
  • Proven stability through standard tests such as aging, freeze/thaw cycles, and dispersibility assessments
Technology readiness level

The encapsulation technology has reached Technology Readiness Level 6. Initial trials and validation processes have been completed, with future testing focused on compatibility screenings and iterative optimization based on standard stability tests. Partnerships are sought to support industrial process development and scale-up efforts.


About NANOMNIA

Nanomnia is a biotechnology SME founded in 2017 that specializes in the development of bio-compatible, bio-degradable, and microplastic-free encapsulation technologies. The company designs, synthesizes, and tests organic micro- and nano-formulations for active ingredients, providing solutions that protect against environmental degradation, improve stability and bioavailability, and allow for controlled release. Utilizing a state-of-the-art laboratory equipped with tools such as HPLC, mass spectrometry, and 3D bioprinting, Nanomnia helps clients in the agrochemical, cosmetic, pharmaceutical, nutraceutical, and advanced materials sectors transition away from microplastic additives in compliance with upcoming European regulations. Their R&D and operational model includes licensing registered patents, forming joint ventures, and offering ad-hoc analytical chemistry services to optimize product efficacy and sustainability.

For customers and partners, Nanomnia provides critical support in navigating the transition to sustainable industrial practices by reducing treatment dosages and environmental impact. By encapsulating active principles, the company enables clients to achieve greater specificity in their applications, such as improving the energy conversion efficiency of photovoltaic panels or enhancing the stability of biopesticides. The firm acts as an innovation partner, helping companies test, patent, and bring high-potential, sustainable products to market. Nanomnia has been recognized with numerous industry awards for its agritech and sustainability efforts and continues to collaborate with academic institutions like the University of Verona on advanced biotechnology projects.

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