Biobased dendrimer encapsulation platform for controlled-release pesticide delivery

Overview

This technology addresses a key limitation of essential oil-based biopesticides: their high volatility, which shortens field efficacy and increases environmental losses. By encapsulating essential oils within dendrimers synthesized from plant biomass, the platform protects the active compounds and enables their controlled release over time. The result is a more sustainable crop protection solution that preserves the biocontrol properties of essential oils while reducing the quantity of active substance needed and limiting off-target environmental impact.

The approach is designed for agro-industry partners seeking greener alternatives to conventional pesticides and for formulation companies interested in biobased delivery systems.

Technical specifications

• Dendrimer carrier: Third-generation glycerodendrimers (GD-PPI-3) prepared from plant biomass, offering a renewable and biobased encapsulation matrix.
• Active ingredient: Essential oils with demonstrated pesticide properties, initially validated using cinnamon essential oil rich in trans-cinnamaldehyde.
• Encapsulation performance: 216.49 mg of trans-cinnamaldehyde encapsulated per gram of GD-PPI-3 from a starting concentration of 479 mg/g, confirming high loading capacity.
• Release profile: Initial burst release followed by gradual, sustained release of the active substance, which is well suited to pesticidal field applications.
• Biocidal efficacy: Complete inhibition of Arabidopsis thaliana seed germination achieved at a minimal essential oil concentration of 12.5 mg/L.
• Scalability pathway: Extension to additional capsule types and other essential oils with targeted pesticidal effects, supported by planned life cycle assessment (LCA) studies for each encapsulation system.

Technology readiness level

The encapsulation system has been validated at laboratory scale, with demonstrated performance in encapsulation yield, controlled release kinetics, and biological efficacy against seed germination. The next stage involves larger-scale testing and in-field trials, alongside diversification of capsule chemistries and essential oil actives. Life cycle assessment studies are planned to quantify environmental benefits and guide further development toward commercial deployment.