Biochemical herbicide targeting weeds

Technology
In development
University
Scouted & summarized by Halo AI

UFSM is developing a biochemical herbicide derived from the fungus Fusarium fujikuroi as a sustainable alternative to synthetic chemicals like glyphosate. The project aims to provide an effective, environmentally friendly solution for weed control that degrades easily in the soil. Currently in the development and scaling phase, the research is conducted in partnership with the private sector to facilitate industrial production and regulatory registration in Brazil.

Overview

The Universidade Federal de Santa Maria (UFSM) is developing a biochemical herbicide derived from the fungus Fusarium fujikuroi. This project aims to create a sustainable, biotechnological alternative to conventional chemical herbicides like glyphosate, which are increasingly associated with environmental degradation and the development of weed resistance. By leveraging microbial processes, this solution seeks to provide an effective tool for weed control that is more easily degraded by soil microorganisms, thereby reducing long-term environmental impact and residual damage to ecosystems.

Technical specifications

The bioherbicide is produced through advanced biotechnological processes, specifically utilizing the fungus Fusarium fujikuroi. Key technical aspects include:

  • Bioprocess development: The research focuses on optimizing fermentation processes, including submerged and solid-state fermentation, to produce active biomolecules.
  • Formulation and scaling: The project involves developing methods to scale production from laboratory settings to pilot-scale, ensuring the process is economically viable for industrial application.
  • Mechanism of action: The product utilizes specific enzymes and metabolites that interfere with weed development, offering a selective and effective alternative to synthetic chemicals.
  • Environmental profile: Unlike stable chemical molecules, the bio-based components are designed to be readily degraded by soil-dwelling microorganisms.
Technology readiness level

The technology is currently in the development phase, estimated at TRL 4-5. The project has successfully demonstrated promising results in greenhouse trials, with efficacy levels comparable to or exceeding glyphosate in certain conditions. Current efforts are focused on overcoming the primary bottleneck of scaling the production process, producing pioneer batches, and conducting larger-scale field tests to facilitate future industrial transfer and...

Generated Oct 8, 2026. Please verify key information.

About Universidade Federal de Santa Maria

UFSM is a comprehensive, multi‑campus public research university based in Santa Maria, Rio Grande do Sul. Industry engages via the university’s innovation, science and technology park and two incubators that co‑locate startups with faculty and students; capstone projects can be completed inside resident companies. Clinical collaboration is enabled by the University Hospital of Santa Maria within Brazil’s federal hospital network. Research is supported by competitive funding from national and state agencies such as CNPq, CAPES, FINEP and FAPERGS. A dedicated technology transfer office manages IP, licensing and university–industry agreements, under a pro‑rectory focused on innovation and entrepreneurship.

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