Bioprocessing & biocatalysis group advancing clostridia and lignocellulosic fermentation for butanol and other biofuels/chemicals
The Ohio State University, led by Professor Shang-Tian Yang, specializes in bioprocessing, metabolic engineering, and biocatalysis, focusing on sustainable biofuel and chemical production from lignocellulosic biomass. Their research includes engineering Clostridium strains for efficient butanol biosynthesis, advancing renewable biofuels, and developing integrated bioprocesses for value-added products.
The Ohio State University hosts the Shang-Tian Yang Group, a leading research team in bioprocessing and bioengineering, with a focus on metabolic engineering, fermentation scale-up, and biocatalysis for biofuels and chemicals derived from lignocellulosic feedstocks. Their work includes engineering Clostridium strains to enhance biobutanol production, addressing challenges like low yield and process instability, supported by significant funding such as a $2.5 million grant from the DOE. The group also explores integrated bioprocess development for sustainable biofuel production, aiming to create economically viable and environmentally friendly solutions for the industry. Their research has broad applications in biofuel production, chemical manufacturing, and industrial biotechnology.
About The Ohio State University
The Ohio State University is a comprehensive public land‑grant research university in Columbus, serving one of the nation’s largest student populations and a broad research enterprise. Industry partners engage through an integrated academic medical center for clinical translation, a campus‑adjacent innovation district for co‑located projects, and a statewide extension network that pilots solutions across Ohio. Corporate engagement provides a single front door for sponsored research, talent pipelines, and streamlined agreements. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, USDA, DoD, and NASA. A dedicated technology transfer office and venture support help protect IP, license technologies, and launch startups.
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