Emulsion crosslinked microencapsulation system for probiotics in low ph beverages
Innovative microencapsulation system using chitosan and gelatin to protect and deliver probiotics in acidic beverages while maintaining sensory properties and ensuring viability.
Overview
The Ohio State University presents an innovative microencapsulation system designed to protect and deliver probiotics in low pH beverages. Utilizing chitosan and gelatin, this system enhances the stability and viability of probiotics, ensuring their effective release in the gastrointestinal tract. The encapsulation method promises to maintain the sensory properties of beverages while promoting the health benefits of probiotics.
Technical specifications
Key features:
- Chitosan and Gelatin Polymers: Provides stability during processing and storage, and controlled release in the gastrointestinal environment.
- GRAS-Approved Materials: Streamlines regulatory approval due to the use of FDA-recognized safe materials.
- Sustained Release Mechanism: Gelatin dissolves in the stomach for initial release, while chitosan offers continued protection and viability.
- Customization Potential: The system allows for optimization of polymer layering, culture types, and particle sizes for maximum encapsulation efficiency.
Technology readiness level
This technology is currently at TRL 3, indicating it is in the experimental proof of concept stage. Future research will focus on optimizing the encapsulation process and validating its efficacy in real-world applications.
About The Ohio State University
The Ohio State University is a comprehensive public land‑grant research university in Columbus, serving one of the nation’s largest student populations and a broad research enterprise. Industry partners engage through an integrated academic medical center for clinical translation, a campus‑adjacent innovation district for co‑located projects, and a statewide extension network that pilots solutions across Ohio. Corporate engagement provides a single front door for sponsored research, talent pipelines, and streamlined agreements. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, USDA, DoD, and NASA. A dedicated technology transfer office and venture support help protect IP, license technologies, and launch startups.
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