Encapsulation of probiotic bacteria in thermostable insulating hydrogels
A novel hydrogel matrix for encapsulating probiotic bacteria, enhancing survival during gummy production. This thermostable solution improves viability by leveraging bacterial cellulose and nanomaterials.
Overview
This innovative solution involves the encapsulation of probiotic bacteria within a thermostable natural nanocomposite hydrogel matrix. The primary goal is to enhance the survival of probiotics during the production of probiotic gummies. The hydrogel matrix, inspired by the survival mechanisms of Kombucha-producing bacteria, offers high thermal stability and insulation properties, ensuring that probiotics remain viable through the manufacturing process.
Technical specifications
Key features:
- Material Composition: Utilizes bacterial cellulose combined with alginate nanoparticles to form a hydrogel matrix.
- Survival Enhancement: Provides high hygroscopicity and thermal stability, protecting probiotics from harsh production conditions such as high temperatures and UV radiation.
- Application Process: Involves optimizing the entrapment of probiotics in the matrix, followed by incorporation into the gummy manufacturing process.
Technology readiness level
This technology is currently at TRL 4, having undergone laboratory validation. Future steps include optimizing entrapment processes and scaling the incorporation of the hydrogel matrix into gummy production.
About University of North Carolina, Greensboro
UNC Greensboro is a comprehensive public research university in Greensboro, North Carolina, within the UNC System, offering broad liberal arts and professional programs. Industry collaboration is anchored by Gateway Research Park—a joint venture with NC A&T—that co-locates companies with university labs and the Joint School of Nanoscience and Nanoengineering, providing access to advanced characterization and fabrication facilities. The university’s Piedmont Triad location offers ready connections to a regional industry and supply‑chain hub. Research is supported by competitive federal awards from agencies such as the National Science Foundation and National Institutes of Health. A dedicated technology transfer office assists with IP, licensing, and startup formation.
Inquire about this partnering listing
Industry applications
delivered to your inbox.