Encapsulation of probiotics using zein-based amphiphilic protein
Akorn's proprietary zein-based encapsulation technology enhances the viability of probiotics in gummy supplements. This solution offers high encapsulation efficiency and is GRAS approved, making it ideal for stabilizing probiotics during production and storage.
Overview
Akorn introduces a cutting-edge encapsulation technology utilizing a zein-based amphiphilic protein to enhance the stability and viability of probiotics in gummy supplements. Zein, a plant-derived protein, is known for its robustness under high temperatures, varying pH levels, and shear stress, which are typical during gummy manufacturing. This technology aims to protect sensitive probiotics like Lactobacillus and Bifidobacterium species, ensuring they remain viable throughout production and storage without affecting the manufacturing process or product quality.
Technical specifications
- Key Features:
- Zein's excellent stability under challenging conditions like high temperatures and varying pH levels
- Water-soluble and amphiphilic properties of zein allow for high encapsulation efficiency and loading capacity
- GRAS status in the US and approval as a food ingredient in the EU and Australia
- Applications:
- Effective for probiotic gummy supplements
- Potential stabilization of other fragile bioactive compounds like antibiotics and antioxidants
- Validation Procedures:
- Testing encapsulation efficiency and probiotic loading capacity under simulated gummy processing conditions
- Evaluating probiotic viability in different storage conditions
Technology readiness level
This technology is at TRL 3, indicating that it has been proven in a laboratory setting. Future validation steps include testing in simulated gummy production environments to further refine and optimize the system's performance parameters.
About Akorn
Akorn Technology is an AgriTech startup that develops multi-functional, 100% natural edible coatings for fresh fruits and vegetables. Founded in 2019 and based in Berkeley, California, the company utilizes a proprietary technology derived from non-GMO corn, rice, and sunflower byproducts to create protective barriers. These water-based coatings work by regulating oxygen exchange, minimizing moisture loss, and inhibiting the growth of bacteria and mold. Designed as a drop-in solution for packers and growers, the product integrates into existing supply chain equipment through spraying or dipping processes without requiring branding concessions or synthetic chemicals.
By extending the shelf life of produce by two to three times, Akorn aims to reduce food waste throughout the supply chain by 50%. This technology addresses critical losses in fresh produce transportation, particularly in regions with limited infrastructure. The company has demonstrated effectiveness across various crops, including mangoes, avocados, apples, and citrus, by enabling producers to maintain harvest-fresh quality for longer durations, thereby increasing market access and profitability while promoting sustainable food systems globally.
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