Encapsulation technologies for lipophilic compounds using natural materials
Innovative micro and nano-encapsulation technologies utilizing natural materials for enhanced stability and controlled release of lipophilic compounds in various sectors like food, nutraceuticals, and cosmetics.
Overview
Sphera Encapsulation has developed cutting-edge encapsulation technologies focusing on micro and nano-scale applications. Utilizing natural materials, these technologies enhance the stability and controlled release of lipophilic compounds. The emulsion-based technology offers variable sizes from nano (50 nm) to micro (5-6 µm), while the coacervation technology produces larger particles (5-20 µm), both enabling sustained release and resistance to external stimuli. Applications span across food, nutraceuticals, agro-chemistry, smart materials, and cosmetics.
Technical specifications
- Emulsion-based technology: Capable of producing particles from 50 nm to 5-6 µm with customizable shell layers for sustained release and enhanced resistance to stimuli.
- Coacervation technology: Produces particles ranging from 5 to 20 µm with stability suitable for applications like concrete.
- Use of natural materials: Avoids harmful cross-linkers, focusing on sustainability and improving shell resistance.
Technology readiness level
This encapsulation technology is currently at TRL 4, indicating that it has been validated in a laboratory setting and shows potential for further development and customization in various fields.
About Sphera Encapsulation
Sphera Encapsulation is an Italian biotechnology company founded in 2016 that specializes in micro- and nano-encapsulation technologies. Headquartered in Verona, the firm develops protective barriers for sensitive active ingredients, employing various methods such as spray drying, fluid bed, coacervation, and ionic gelation. These technologies are designed to enhance the stability, bioavailability, and handling of substances by protecting them from degradation, heat, moisture, and oxidation. The company is known for proprietary innovations like SpherAQ, which improves the functionality and solubility of lipophilic compounds in aqueous environments.
The company serves diverse industrial sectors, including functional foods, nutraceuticals, pharmaceuticals, cosmetics, and agrochemistry. By providing customized encapsulation solutions, Sphera helps partners improve product performance and address challenges such as targeted delivery, ingredient waste, and environmental impact. Their work is characterized by a commitment to sustainable, ecological formulations and the use of natural substances. The company was established by co-founders Martina Vakarelova and Francesca Zanoni, with support from the University of Verona, and has since expanded its operations to address complex formulation needs across international markets.
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