Hair-growth-promoting effects of eggshell membrane peptides
Discover the potential of eggshell membrane peptides for hair growth and anti-aging with our advanced screening model. Utilizing human dermal papilla cells and ex vivo hair follicles, we aim to develop innovative cosmetic products.
Overview
This innovative research explores the potential of eggshell membrane peptides (EMPs) and collagen peptides (CPs) for promoting hair growth and combating aging. By establishing a hair follicle aging model using human dermal papilla cells and ex vivo hair follicles, this study aims to screen natural compounds with significant effects on hair follicle cell proliferation, migration, and anti-aging mechanisms. The ultimate goal is to facilitate the development of cutting-edge anti-aging cosmetic products.
Technical specifications
- Hair follicle aging model: Utilizes human dermal papilla cells (hDPCs) and ex vivo human hair follicles.
- Medium-to-high throughput screening platform: Automated liquid handling system capable of screening over 200 compounds daily.
- Efficacy verification: Tests hair-growth-promoting and anti-aging effects compared with positive controls, including minoxidil.
- Peptide preparation: Enzymatic hydrolysis and ultrafiltration to prepare EMPs and CPs.
- Concentration testing: Effects of peptides tested at concentrations ranging from 0.1 to 100 μg/mL.
- Mechanism analysis: Includes nuclear translocation of β-catenin and expression of p16 mRNA.
Technology readiness level
The technology readiness level is currently at stage 4, indicating that the research and validation are at the laboratory testing phase. Future steps include optimization and preliminary clinical trials to further validate the efficacy of the identified compounds.
About Huazhong Agricultural University
Huazhong Agricultural University is a public research university in Wuhan with a strong focus on agriculture and the life sciences, coupling fundamental inquiry with field‑ready application. Industry engages through co‑located experimental farms and controlled‑environment facilities, shared cores for genomics and phenotyping, and biosafety‑equipped laboratories. Field stations and demonstration bases across the region enable multi‑season trials and scale‑up with growers and agri‑tech partners, while proximity to Wuhan’s high‑tech corridor and logistics hub streamlines collaboration. Research is supported by competitive national and provincial funding, including the National Natural Science Foundation of China and related ministries. A dedicated technology transfer office facilitates IP management, licensing, and enterprise partnerships.
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