Minimally invasive biosensor for real-time micronutrient monitoring
A minimally invasive biosensor platform designed to detect and monitor micronutrient levels in biofluids. By integrating advanced biorecognition elements with novel signal transduction, it enables real-time monitoring, supporting early diagnosis and personalized interventions.
Overview
The minimally invasive biosensor platform offers a groundbreaking solution for accurately detecting and monitoring micronutrient levels in human biofluids, such as blood and interstitial fluid. By leveraging advanced biorecognition elements and innovative signal transduction techniques, this platform enables real-time monitoring of micronutrient status. This advancement supports early diagnosis of deficiencies and facilitates personalized nutrition and medical interventions, addressing a critical gap in health management by providing rapid, accessible diagnostics.
Technical specifications
Key features:
- Utilizes a novel aptamer-nanoparticle interface to enhance sensitivity and specificity
- Capable of real-time, point-of-care monitoring in biofluids
- Designed for integration into a portable system for practical usability
- Undergoes rigorous validation for limit of detection (LOD), linear range, and selectivity
- Performance verified against standard analytical methods like LC-MS to ensure accuracy and reproducibility
Technology readiness level
The biosensor platform is at Technology Readiness Level 4, indicating that it has been validated in a laboratory setting. The next steps include optimizing the design for sensitivity and specificity, integrating into a portable system, and validating its performance in simulated clinical environments.
About University of Tennessee, Knoxville
UT offers a partnership model that reduces risk, accelerates time-to-value, and supports long-term growth strategies for industry—providing an attractive platform for companies seeking to formalize collaboration and establish a long-term presence in the East Tennessee region. By aligning institutional investment with regional and national priorities, UT provides a stable and effective platform for industry collaboration, technology deployment, and sustained economic impact.
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