Mycotoxin detection in grain extracts using LC-HRMS
Advanced LC-HRMS technology is employed for the detection and quantification of mycotoxins in grain extracts, offering high selectivity and sensitivity for a wide range of compounds. This method improves accuracy in monitoring contamination levels crucial for food safety.
Overview
The detection of mycotoxins in grain extracts is crucial for ensuring food safety, as these toxic compounds can persist through processing and storage. Leveraging Liquid Chromatography-High-Resolution Mass Spectrometry (LC-HRMS), this solution provides a comprehensive method for identifying and quantifying a broad spectrum of mycotoxins. LC-HRMS is renowned for its high selectivity and sensitivity, allowing for the detection of multiple mycotoxins simultaneously, even at low concentrations.
Technical specifications
- Detection System: Utilizes UPLC-XEVO-G2-XS-ESI-QTOF with an ACQUITY C18 column, capable of operating in both positive and negative ionization modes depending on the mycotoxin being analyzed.
- Quantification Software: Employs QuanLynx software to analyze raw files, generate calibration curves using standard samples, and quantify mycotoxin concentrations with high precision.
- Sample Analysis: Includes comprehensive analysis of sample and standard raw files, identification of compound peaks, and computation of responses which are stored in a dataset for further analysis.
Technology readiness level
This technology has achieved a TRL of 6, indicating that it has been demonstrated in a relevant environment and is moving towards system/subsystem development for broader applications.
About International Crops Research Institute for the Semi-Arid Tropics (ICRISAT)
ICRISAT is a nonprofit international agricultural research center in the CGIAR system, headquartered in Hyderabad, India, with regional hubs and research stations across sub‑Saharan Africa and a global genebank. It engages companies through seed‑industry consortia for hybrid parents and structured public–private breeding partnerships, supported by multi‑location trials. An Agribusiness & Innovation Platform, with a technology business incubator and food‑processing pilot facilities, helps de‑risk scale‑up and product development. Research is backed by CGIAR funding and international donors including USAID, the Bill & Melinda Gates Foundation, and multilateral banks. An in‑house IP facilitation cell and partnership office streamline licensing and collaboration.
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