Patented microbiome-driven nitric oxide technology for skin health
Qinino® is a patented, microbiome-driven technology designed to stimulate the natural bacterial pathway for nitric oxide (NO) generation in the skin. By combining nitrate with a specialized biopolymer, Qinino® is designed to deliver nitrate to nitrate-converting bacteria in microbiome-rich environments, enabling controlled and sustained local NO generation.
The skin microbiome represents a promising target for this approach. Qinino® is designed to work with the naturally occurring bacterial ecosystem of the skin rather than simply delivering a conventional active ingredient to the skin. This creates opportunities for the development of next-generation topical solutions focused on skin health, barrier support, skin recovery and microbiome-related applications.
Prototype products have already been developed, NO-ceuticals is seeking strategic partners for further research, formulation development, validation and commercialization of Qinino®-based skin applications. The technology can potentially be incorporated into creams, gels, serums or other topical delivery formats, depending on the target application.
About NO-ceuticals
NO-ceuticals B.V. is a Netherlands-based biotechnology startup dedicated to optimizing human health, performance, and longevity through microbiome-driven nitric oxide (NO) solutions. Founded by a team with roots in medicine, the company leverages a patented ingredient called Qinino®, which is designed to enhance the bacterial nitric oxide route. By activating nitrate-converting bacteria throughout the body, rather than just in the mouth, the technology aims to boost both local and systemic nitric oxide production. The company operates as a remote-first organization and focuses on science-backed innovation to develop natural and effective health solutions.
The company’s work is significant for individuals and partners seeking advanced, evidence-based approaches to wellness and metabolic health. By focusing on the body's own mechanisms for nitric oxide generation, NO-ceuticals addresses a critical component of physiological health. The startup is currently engaged in ongoing research and development, with initial studies yielding promising results. They are actively building a strategic framework for future clinical validation and commercial application, while seeking collaborations with research and innovation partners to bring their proprietary ingredients to a global market.
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