Protein signal amplification platform (PSA)
Our PSA platform represents a paradigm shift in diagnostic testing. It enables room-temperature, nanogram level detection in less than 5 minutes from sample prep to results and operates without the need for enzymes or refrigeration. Additionally, it is compatible with multiple targeting probe technologies (antibodies, nucleic acid oligos, aptamers, fab fragments, peptides, etc...) as compared to most other molecular detection technologies. Our system achieves an ultra-low cost per test due to roughly 90% of the platform components being target agnostic, minimizing delays associated with adapting the assay to new targets. This modular base platform also allows for for rapid adaptation to emerging pathogens and new biomarkers, eliminating the logistical, financial, and technical burdens associated with developing conventional molecular diagnostics, while maintaining both sensitivity and specificity.
Our platform has completed proof-of-concept testing showing qualitative results in as little as 1 minute. Our next step, and the focus of our current fundraising efforts is to develop our MVP and are planning on this being in the veterinary testing markets to minimize the time and costs associated with human testing regulatory requirements and allow us to establish a beachhead to showcase our technology.
About Bench in a Box Technologies
Bench in a Box Technologies is developing a diagnostic platform designed to provide rapid, portable molecular testing for field and low-resource environments. Its core innovation is a patent-pending Protein Signal Amplification (PSA) platform, which enables specific molecular detection without the need for electricity, refrigeration, or complex laboratory infrastructure. The process uses specialized probes and a capture interface to immobilize targets, followed by a universal reporter solution that produces a distinct color change in under five minutes. By eliminating the requirement for traditional PCR/qPCR thermocycling, the technology offers a flexible approach to detection that can incorporate various molecules, such as antibodies, as a targeting mechanism.
This platform is intended to democratize access to high-quality diagnostics across diverse sectors, including clinical healthcare, veterinary medicine, and environmental monitoring. By focusing on point-of-care solutions, the company aims to overcome the logistical barriers often associated with diagnostic testing in remote or rural areas. The organization is currently led by a team with expertise in molecular diagnostics, pharmaceutical R&D, and scientific logistics, and it is actively pursuing investment to scale its development and commercialization efforts. Bench in a Box Technologies is based in Bay City, Michigan.
Inquire about this partnering listing
Looking for
Industry applications
delivered to your inbox.