Innatrix, Inc. has identified nematode genes that, when silenced, lead to an 80% reduction in the number of actively feeding nematodes on soybean roots.
We have manufactured good quantities of the RNAi molecules used for greenhouse and field testing. We established two effective RNAi delivery systems for soybean roots, also demonstrated great nematode control in the greenhouse using in furrow application. More importantly, we saw RNAi has generation effects, which indicated RNAi is not only controlling one generation of SCN cycle, but also controls the next generation of nematodes. This way, this solution may eventually reduce the SCN populations in the field conditions. After treating soybean plants with RNAi solutions in the field trial, we observed RNAi delayed nematode progression inside soybean roots. Currently, we are working with our partners to develop a RNAi based seed treatment product. We anticipate finding a commercial partner to speed up the product development process. Simultaneously, we had pre-submission meeting with EPA regulators, and we are working with our regulatory consultant to perform toxicology studies, and start preparing a regulatory package for EPA submission soon.
Innatrix is a North Carolina-based biotech company founded in 2012, specializing in sustainable biopesticides and innovative crop protection solutions.