Senseup dsrna-based biopesticides for effective fungal control

Overview

SenseUP presents an innovative dsRNA-based biopesticide designed to combat Pyricularia oryzae, the fungus responsible for rice blast disease. The product leverages the natural soil bacterium Corynebacterium glutamicum, which is evolved to encapsulate significant amounts of double-stranded RNA (dsRNA). This dsRNA targets specific fungal transcripts via the RNA interference (RNAi) pathway, effectively inhibiting fungal growth. The solution is non-toxic, biodegradable, and traceless, making it an environmentally friendly alternative to traditional chemical pesticides.

Technical specifications

Key features:

• Utilizes Corynebacterium glutamicum to encapsulate dsRNA, improving stability and reducing manufacturing costs.
• Manufactured through well-established aerobic fermentation, heat inactivation, and drying processes.
• Long-term storable and distributable in paper bags, applied via conventional spraying methods.
• Proven efficacy in lab trials, with rice plants showing increased resistance to Pyricularia oryzae.

Technology readiness level

This biopesticide is at Technology Readiness Level 5, having demonstrated proof of concept in laboratory trials. Future validation plans include greenhouse and field trials to further confirm efficacy and optimize the formulation.