Structure-guided modeling of insect sodium-channel ligands and resistance

Technology
University

Researchers at McMaster University used an AlphaFold2 model of the insect sodium channel to analyze pyrethroid binding and resistance-relevant channel features. The work is especially relevant for resistance management and rapid screening of new sodium-channel chemotypes.


About McMaster University

McMaster University is a comprehensive, research‑intensive public university in Hamilton, Ontario, known for collaborative, problem‑driven scholarship and strong partnerships with healthcare and industry. A research and technology park adjacent to campus co‑locates corporate R&D with faculty labs, while an established engineering co‑op connects companies with talent and applied expertise. Deep integration with regional hospital systems enables clinical trials, real‑world evidence generation, and translational studies at scale. Research is supported by competitive funding from NSERC, CIHR, SSHRC, and the Canada Foundation for Innovation. A dedicated technology transfer office streamlines IP strategy, contracting, and commercialization for industry partners.

Halo home
Partner smarter. Move faster.
Get new partnering requests
delivered to your inbox.