Triggered swelling microcapsules for controlled release of active ingredients

Overview

Trucapsol LLC presents an innovative microencapsulation technology that leverages spray drying to produce microcapsules with pH-triggered swelling properties. This technology is designed to encapsulate active ingredients, ensuring their stability and controlled release in response to specific pH levels. The microcapsules remain impermeable in acidic environments but swell and release their contents when exposed to higher pH levels or upon dilution. This characteristic makes the technology particularly suitable for applications in the beverage industry and pharmaceuticals, where precise delivery of active ingredients is crucial.

Technical specifications

• Encapsulation process: Utilizes a combination of sorption-based encapsulation at room temperature and spray drying to achieve over 50% encapsulation efficiency.
• Trigger mechanism: Designed to remain stable at pH 3 and release active ingredients above pH 7 or upon dilution.
• Adaptability: The process can encapsulate various actives, including enzymes, and protect them during high-temperature manufacturing processes.
• Prototyping and testing: Includes accelerated stability testing and compatibility assessments with target formulations.

Technology readiness level

Currently at TRL 4, this technology has been validated at the pilot scale with successful prototype development. Future plans include further prototyping, stability testing, financial viability analysis, and IP filings to advance the technology towards commercial readiness.