PG
Gismo Therapeutics Inc.
Small molecules that bind heparan sulfate with high affinity, developed as PET ligands for lysosomal storage disease.
Sponsored researchConceptualSupplier
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Updated Sept 30, 2026
Medical imaging covers the tracers, instruments and software used to see inside the body and read what comes back. On Halo, the solutions cover PET ligands for lysosomal disease, tracers for the brain, optical imaging at the bedside, and reading images with AI. Sign up to search the full network and post your specific need.
PET ligands for lysosomal disease
PG
CJ
Australian National University
Fragment-based design of selective heparanase binders for PET imaging of the lysosome.
Sponsored researchConceptualUniversity
GB
Hebrew University of Jerusalem
Probes that bind cathepsin proteases covalently, letting PET follow lysosomal activity.
Co-developmentConceptualUniversity
VF
The University of Queensland
PET ligands for the lysosomal enzymes IDS, IDUA, SGSH and NAGLU.
Sponsored researchConceptualUniversity
EA
Fluorine-18 ligands aimed at senescence markers and lysosomal storage features.
Sponsored researchConceptualUniversity
VN
R.V. College of Engineering
A computationally designed ligand for LAMP-1, the lysosomal membrane protein.
Sponsored researchConceptualUniversity
EY
University of Liverpool
High-affinity heparan sulfate binding peptides derived from FGF binding sites.
Sponsored researchConceptualUniversity
Tracers for the brain
WP
Vanderbilt University Medical Center
A PET radioligand built on ergothioneine, imaging neuroinflammation with no biopsy.
Sponsored researchIn developmentUniversity
ZT
Washington University in St. Louis
PET tracers for the S1PR5 receptor in central nervous system disease.
Sponsored researchConceptualUniversity
AD
Miniaturized synthesis and label-free screening feeding cassette-dose PET studies in mice.
Sponsored researchConceptualUniversity
UO
University of Alberta
A compound that cyclizes peptides and chelates radiometals, for peptide-based theranostics.
LicensingConceptualUniversity
Optical imaging at the bedside
University of Alabama, Huntsville
A low-cost polarized microscope that reads skin collagen with no incision.
Sponsored researchIn developmentUniversity
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Who is working on medical imaging
Organizations in medical imaging
Universities, startups, and suppliers with solutions in medical imaging.
Medical imaging organizations
Innovators in medical imaging
Researchers and inventors advancing medical imaging.
Medical imaging expertsAbout medical imaging
Medical imaging on Halo is unusually weighted toward molecular imaging: a large body of PET ligand chemistry for lysosomal disease sits alongside optical instruments built to work outside a scanner room. On Halo it spans six groups, including PET ligands for lysosomal disease, tracers for the brain, and optical imaging at the bedside.
Stage of development. Work on medical imaging on Halo comes mostly from university programs. 41% of the solutions are in market. University of Tennessee, Knoxville and University of Alabama, Huntsville have the most, followed by University of Alberta. Co-development and sponsored research are the usual partnering routes, and about 44% of the solutions that state terms offer licensing.
Three trends in medical imaging on Halo
Chemistry aimed at the lysosome. Seven solutions are PET ligands for lysosomal biology, which is more than any other single target on the page. They bind heparan sulfate, heparanase, cathepsins and LAMP-1, and several carry fluorine-18. It is an unusual concentration for a page that also holds microscopes and AI.
Imaging that leaves the scanner room. A second cluster is portable by design: a low-cost polarized microscope reading skin collagen, a time-resolved spectroscopy system for cerebral monitoring, and a miniature MALDI-2 mass spectrometer under an ARPA-H award. The constraint being designed against is the room, not the physics.
Models trained on what is missing. The AI solutions are less about accuracy than about data. One generates balanced cancer cohorts to fix imbalance in the real ones, another annotates to clear the ground-truth bottleneck, and a third computes over encrypted pixels so the data never has to move.
366organizations
383solutions listed
79%from university labs
41%in market
Frequently asked questions
What is medical imaging?
Medical imaging covers the tracers, instruments and software that produce a picture of the inside of the body and interpret it. It spans PET and SPECT radioligands, contrast agents and fluorescent probes, optical and spectroscopic instruments, and the machine learning that reads what they produce. Imaging device makers, radiopharmaceutical developers and hospital radiology groups are the users.
What are examples of medical imaging?
Four examples of medical imaging solutions on Halo include:
- Small molecules that bind heparan sulfate with high affinity, developed as PET ligands for lysosomal storage disease. (Gismo Therapeutics Inc.)
- A PET radioligand built on ergothioneine, imaging neuroinflammation with no biopsy. (Vanderbilt University Medical Center)
- A low-cost polarized microscope that reads skin collagen with no incision. (University of Alabama, Huntsville)
- Segments the pediatric eye on head CT and detects retinal hemorrhage automatically. (University of Tennessee, Knoxville)
Which companies and suppliers are developing medical imaging?
There are 366 organizations with medical imaging solutions on Halo, 79 of them universities and research institutions. Among them are Gismo Therapeutics Inc., Australian National University, and Hebrew University of Jerusalem. Most offer co-development or sponsored research. Sign up to see every organization working in the area and to send them your specific need.
How do I find medical imaging research partners?
Browsing medical imaging solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
What are R&D teams looking for in medical imaging?
Over the past 12 months, R&D teams on Halo have posted these medical imaging needs:
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