YC
Janus base nanoparticles carrying mRNA and gene editing tools to a chosen tissue.
In-development
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Updated Nov 2, 2026
Personalized medicine covers the delivery, dosing and profiling technologies that fit a treatment to one patient and not a population. On Halo, the solutions cover targeted gene and RNA delivery, printed and variable dosing, omics platforms for target selection, and patient-derived disease models. Sign up to search the full network and post your specific need.
Targeted gene and RNA delivery
YC
Ronald Raines
Massachusetts Institute of Technology · University
Endosomolytic peptides that get mRNA out of the endosome and into the cytosol.
In-development
KX
University of Michigan
A biodegradable cationic polymer vector with high transfection efficiency in vivo.
In-development
Printed and variable dosing
JS
InfraTrac, Inc · Startup
3D printed polypills combining several doses in one geometry, for variable-dose regimens.
In-development
RC
Université de Liège · University
Filaments loaded with active ingredients, so a printer can make the dose.
In-development
MS
Universität für Bodenkultur Wien · University
Laser-powder bed fusion with responsive materials, for dose forms that release on a cue.
In-development
Omics platforms for target selection
CC
Washington University in St. Louis
Multi-tissue profiling across genomics, transcriptomics, proteomics and metabolomics to find causal targets.
Sponsored researchIn-development
Gnaneshwar Yadav
Captures translating mRNA across organs to see what a drug is actually doing where.
Sponsored researchIn-development
Bernd Nebel
Innophore GmbH · Startup
Cloud search for off-target binding pockets across the human proteome.
LicensingIn-development
Patient-derived disease models
OB
Technion - Israel Institute of Technology · University
iPSC cardiomyocytes carrying the patient's own cardiomyopathy mutation.
In-development
Consumer biomarker platforms
AB
Family Care Clinic · Startup
A home urine test read by smartphone that tracks urinary biomarkers for remote patient monitoring.
Sponsored researchIn-development
Seun Ola
VII Technologies, Corp · Startup
Turns blood biomarkers, biometrics and nutrition data into an individual profile.
Sponsored researchIn-development
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Who is working on personalized medicine
Organizations in personalized medicine
Universities, startups, and suppliers with solutions in personalized medicine.
Personalized medicine companies
Innovators in personalized medicine
Researchers and inventors advancing personalized medicine solutions.
About personalized medicine
Personalized medicine on Halo is practical and not conceptual: carriers that reach a named organ, printed dose forms that can be varied per patient, and omics platforms used to pick a target before any of that starts. On Halo it spans five groups, including targeted gene and RNA delivery, printed and variable dosing, and omics platforms for target selection.
Stage of development. Work on personalized medicine on Halo is split between university programs and companies. 87% are past proof of concept (TRL 4 or higher). Co-development and sponsored research are the usual partnering routes, and about 43% of the solutions that state terms offer pilot engagements.
Three trends in personalized medicine solutions on Halo
Printing the dose. Five solutions make the dose form itself variable. Polypills combine several drugs in one printed geometry, filaments carry the active ingredient into an FDM printer, and laser-powder bed fusion pairs with responsive materials. Personalization gets solved in manufacturing and not in the molecule.
Carriers aimed at one organ. The delivery cluster is organ-specific by design: liver-directed gene therapy for Fabry disease, PBAE nanoparticles with ligands clicked on for a chosen organ, and stabilized particles that combine covalent and electrostatic binding for tissue selectivity. Getting there is treated as the hard part.
Cells that carry the patient's mutation. Three groups supply iPSC-derived cardiomyocytes carrying specific cardiomyopathy mutations. A candidate can be run against the genotype it is meant for before any patient is involved, which is personalization at the testing stage and not the prescribing one.
851organizations
887solutions listed
53%from university labs
87%past proof of concept
Frequently asked questions
What are personalized medicine solutions?
Personalized medicine fits a treatment to one patient and not to a population, through targeting, dosing or profiling. It spans carriers aimed at a named organ, printed and variable dose forms, multi-omic platforms used to pick a target, and patient-derived cells used to test a candidate against the genotype it is meant for. Pharmaceutical developers and diagnostics companies are the buyers.
What are examples of personalized medicine solutions?
Five examples of personalized medicine solutions on Halo include:
- Janus base nanoparticles carrying mRNA and gene editing tools to a chosen tissue. (Eascra)
- 3D printed polypills combining several doses in one geometry, for variable-dose regimens. (InfraTrac, Inc)
- Multi-tissue profiling across genomics, transcriptomics, proteomics and metabolomics to find causal targets. (Washington University in St. Louis)
- iPSC cardiomyocytes carrying the patient's own cardiomyopathy mutation. (Technion - Israel Institute of Technology)
- Turns blood biomarkers, biometrics and nutrition data into an individual profile. (VII Technologies, Corp)
Which companies and suppliers are developing personalized medicine solutions?
There are 851 organizations with personalized medicine solutions on Halo, 122 of them universities and research institutions. Among them are Eascra, Massachusetts Institute of Technology, and University of Michigan. Most offer co-development or sponsored research. Sign up to see every organization working in the area and to send them your specific need.
How do I find personalized medicine research partners?
Browsing personalized medicine solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
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