An automated high-throughput screening platform that identifies small-molecule inhibitors of fungal ATG4, a cysteine protease essential for autophagy in plant pathogens such as Fusarium oxysporum. The BRET-based assay co...
Innovative fungicides, ebselen and its analogs, inhibit fungal autophagy to control rice blast disease. These compounds target Atg4 cysteine protease, disrupting pathogenic processes. Validated in vitro and in planta, th...