Common natural or bio-based diacids include aspartic acid, malic acid, fumaric acid, glutaric acid, succinic acid, malonic acid, and oxalic acid. Common aldo-acid molecules include glyoxylic acid, pyruvic aldehyde acid derivatives, and oxidized sugar aldehyde-acids. While several of these can also be produced petrochemically, they typically fall within the C2–C6 carbon chain range. These shorter-chain molecules are widely incorporated into polyesters, polyamides, hydrogels, and related materials, but can impose inherent limitations on mechanical properties, flexibility, degradation behavior, and processing performance.
Leprino has developed a novel bio-derived, biocompatible polyhydroxy diacid derivative and polyhydroxy aldo-acid derivative, representing a significantly longer carbon chain length than typical bio-based options. This unique structure may enable differentiated properties such as enhanced flexibility, hydrophobicity/hydrophilicity balance, durability, or tunable degradation profiles, attributes that could meaningfully expand functionality in both bioplastics and hydrogels.
Through collaboration with external polymer experts, we aim to uncover how these new molecules perform in diverse polymerization systems and to identify the most promising pathways for future material innovation.
We are looking to collaborate with established companies capable of evaluating and developing polymer systems that incorporate these novel polyhydroxy diacid and polyhydroxy aldo-acid derivatives. The goal is to identify polymer classes, material properties, and application areas where the molecules provide meaningful performance advantages compared to conventional molecules.
While we are open to collaborating with industrial applied-research centers and contract research organizations, priority will be given to established companies with a strategic interest in incorporating novel building blocks into their existing or future commercial material portfolios.
Incorporation of the polyhydroxy diacid and polyhydroxy aldo-acid derivatives into hydrogel networks (synthetic or bio-hybrid)
Novel or differentiated polymer architectures enabled by long-chain polyhydroxy diacid and polyhydroxy aldo-acid derivatives
Unique functionalities achievable with polyhydroxy diacid and polyhydroxy aldo-acid derivatives compared to C2–C6 analogs
Polymerization of the polyhydroxy diacid and polyhydroxy aldo-acid derivatives into biopolymers, polyesters, polyamides, polyurethanes, or other relevant systems
Established company (polymer manufacturer, medical organizations, materials supplier, industrial R&D group, professional applied research institute) with demonstrated experience in polymer development
Ability to conduct polymerization trials and evaluate resulting material properties
Expertise in synthesizing or modifying polymer systems relevant to bioplastics or hydrogels
Benchmarking novel monomers or bio-based building blocks
Commercializing specialty polymers or functional materials
Startups without established manufacturing or polymer R&D capacity
Academic institutions
We are dedicated to producing products and processes that set the standard for excellence. Our commitment to quality means that every product we produce is designed to deliver optimal performance, whether it’s enhancing health and wellness benefits or meeting the precise requirements of specialized applications, such as pharmaceutical tablets and infant formula.
We work closely with our partners to develop innovative solutions that leverage the unique properties of our products and work effectively in their end products.
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