Polyhydroxy diacid and polyhydroxy aldo-acid applications in polymers
  • Background
  • What we're looking for
  • What we can offer you
  • Who we are
  • Q&A

Leprino is seeking established companies with polymer development expertise to evaluate a novel bio-sourced polyhydroxy diacid derivative and polyhydroxy aldo-acid derivative, assess their performance potential, and identify high-value applications in bioplastics and hydrogels.

Background

Common natural or bio-based diacids include aspartic acid, malic acid, fumaric acid, glutaric acid, succinic acid, malonic acid, and oxalic acid. Common aldo-acid molecules include glyoxylic acid, pyruvic aldehyde acid derivatives, and oxidized sugar aldehyde-acids. While several of these can also be produced petrochemically, they typically fall within the C2–C6 carbon chain range. These shorter-chain molecules are widely incorporated into polyesters, polyamides, hydrogels, and related materials, but can impose inherent limitations on mechanical properties, flexibility, degradation behavior, and processing performance.

Leprino has developed a novel bio-derived, biocompatible polyhydroxy diacid derivative and polyhydroxy aldo-acid derivative, representing a significantly longer carbon chain length than typical bio-based options. This unique structure may enable differentiated properties such as enhanced flexibility, hydrophobicity/hydrophilicity balance, durability, or tunable degradation profiles, attributes that could meaningfully expand functionality in both bioplastics and hydrogels.

Through collaboration with external polymer experts, we aim to uncover how these new molecules perform in diverse polymerization systems and to identify the most promising pathways for future material innovation.

What we're looking for

We are looking to collaborate with established companies capable of evaluating and developing polymer systems that incorporate these novel polyhydroxy diacid and polyhydroxy aldo-acid derivatives. The goal is to identify polymer classes, material properties, and application areas where the molecules provide meaningful performance advantages compared to conventional molecules.

While we are open to collaborating with industrial applied-research centers and contract research organizations, priority will be given to established companies with a strategic interest in incorporating novel building blocks into their existing or future commercial material portfolios.

Topics of interest
  • Incorporation of the polyhydroxy diacid and polyhydroxy aldo-acid derivatives into hydrogel networks (synthetic or bio-hybrid)

  • Novel or differentiated polymer architectures enabled by long-chain polyhydroxy diacid and polyhydroxy aldo-acid derivatives

  • Unique functionalities achievable with polyhydroxy diacid and polyhydroxy aldo-acid derivatives compared to C2–C6 analogs

  • Polymerization of the polyhydroxy diacid and polyhydroxy aldo-acid derivatives into biopolymers, polyesters, polyamides, polyurethanes, or other relevant systems

Required qualifications
  • Established company (polymer manufacturer, medical organizations, materials supplier, industrial R&D group, professional applied research institute) with demonstrated experience in polymer development

  • Ability to conduct polymerization trials and evaluate resulting material properties

  • Expertise in synthesizing or modifying polymer systems relevant to bioplastics or hydrogels

Nice-to-have
We're open to experts who have experience with:
  • Benchmarking novel monomers or bio-based building blocks

  • Commercializing specialty polymers or functional materials

What's out of scope
  • Startups without established manufacturing or polymer R&D capacity

  • Academic institutions

Expert location
  • Accepting applications from experts based in all countries

What we can offer you

Compensation
We will provide the polyhydroxy diacid and polyhydroxy aldo-acid derivatives for evaluation. We are open to discussing collaboration structures such as cost-sharing for testing and joint development agreements. If the collaboration identifies compelling applications, we are open to discussing future scaling-up and commercial supply agreements based on mutually beneficial terms.
Facilities and Services
Partners will be welcome to visit our facilities to collaborate with R&D and Operations experts.
Networking
Partners will be actively connected with our innovation team and collaborate with business unit leaders.
Compounds and Reagents
Partners will be provided with our novel diacid in whatever quantities they require.
Expertise
Partners will be able to collaborate with our innovation and operations scientists, engineers, and other experts as needed.
Data
Partners will have access to all technical data necessary to successfully collaborate with us.
Who we are

We are dedicated to producing products and processes that set the standard for excellence.​ Our commitment to quality means that every product we produce is designed to deliver optimal performance, whether it’s enhancing health and wellness benefits or meeting the precise requirements of specialized applications, such as pharmaceutical tablets and infant formula.​

​We work closely with our partners to develop innovative solutions that leverage the unique properties of our products and work effectively in their end products.​

Reviewers
Q&A with Leprino Foods

The Q&A is now closed.

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Q.
Are academic partners definitely out of scope? We have a team of a few PIs with combined expertise in polymer synthesis, hydrogels, and rheology and established collaborations that may fit your needs well.
2
A.
Hi Surita, You're not aout of scope, I would love to see your thoughts. kind regards, Richard
RM
Richard Merrill, VP Innovation, Leprino Foods
May 14, 2026
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