Advanced method for quantitation of mycotoxins using HPLC/LC-MSMS and immunodiagnostics
This solution offers a validated method for accurate quantitation of mycotoxins in corn and wheat using HPLC/LC-MSMS and commercial immunodetection assays. It provides a detailed comparison of analytical chemistry techniques and immunodiagnostics, ensuring reliable detection and quantitation.
Overview
This innovative solution provides a comprehensive method for the quantitation of mycotoxins in corn and wheat. It leverages advanced analytical chemistry techniques, such as HPLC-UV, HPLC-fluorescence, and LC-MS/MS, and compares their effectiveness with commercial lateral-flow immunodetection systems. This dual approach ensures highly accurate and reliable results, making it ideal for agricultural stakeholders who require precise mycotoxin detection.
Technical specifications
- Analytical Techniques: Utilizes HPLC-UV, HPLC-fluorescence, and LC-MS/MS for enhanced sensitivity and specificity.
- Immunodiagnostics: Employs a commercial immunodetection system for quick and efficient lateral flow analysis.
- Validation Parameters: Includes method validation for selectivity, matrix effects, recovery, linearity, precision, and sensitivity.
- Sample Analysis: Compares extracted mycotoxins from corn and wheat using both analytical and immunodetection methods.
- Statistical Analysis: Employs statistical methods such as t-tests, ANOVA, and correlation analyses to ensure accuracy.
Technology readiness level
This solution is at Technology Readiness Level 4, indicating that it has been validated in a laboratory environment and is ready for further development and testing in relevant field conditions.
About Oregon State University
Oregon State University is a comprehensive public research university and Oregon’s land‑grant institution, with a main campus in Corvallis and a statewide footprint. Industry partners tap a statewide Extension network and county offices to pilot and scale solutions with communities and companies across Oregon. A coastal marine science campus in Newport anchors ocean research and provides access to open‑ocean wave‑energy test ranges and grid‑connected infrastructure under development nearby, enabling sea‑to‑shore prototyping. Field stations and university‑managed research forests support long‑term trials and product validation in real‑world environments. A dedicated technology transfer office and the OSU Advantage programs—including the Advantage Accelerator—streamline IP, licensing, startup formation, and industry agreements.
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