Microcystin-producing bacteria and cyanobacteria as biocontrol agents for improved crop yield

Technology
In development
University

A novel biocontrol approach using microcystin-producing bacteria and cyanobacteria to suppress soil fungal pathogens and improve crop yield. Field studies on corn demonstrated increased yields and reduced pathogen presence, with future validation planned for corn and soybean crops.

Overview

This research proposes the use of microcystin-producing bacteria and cyanobacteria as a natural biocontrol strategy to improve crop yield and overall plant health. The hypothesis is that these microorganisms inhibit the growth of oomycete and ascomycete pathogens through the production of extracellular metabolites, leading to reduced soil pathogen presence and improved crop performance. Field studies on corn have demonstrated promising results, including increased yields, enhanced growth, and decreased soil pathogen presence in soils with higher abundance of microcystin-producing bacteria and cyanobacteria.

Technical specifications

Key features:

  • Microcystin-producing bacteria and cyanobacteria are applied to soil, either directly or via dredged sediments
  • These microorganisms produce extracellular metabolites that inhibit oomycete and ascomycete pathogens
  • The approach has been validated in field studies on corn, with 20 sampling locations across two fields
  • Soil health parameters, including bacterial and fungal communities, were measured prior to planting and after harvest
  • Future validation will include greenhouse experiments factorially manipulating microcystin-producing bacteria and cyanobacteria in soils for corn and soybean crops
  • Sequencing efforts will identify soil bacterial and fungal communities to assess the effects of extracellular metabolites
Technology readiness level

This technology is currently at an early stage of development, with promising field study results on corn. The research team is seeking funding support for sequencing efforts to further validate the approach and assess its effects on crop growth and yield. Future studies will focus on greenhouse experiments and the identification of soil bacterial and fungal communities to refine the biocontrol strategy.


About Wright State University

Wright State University is a comprehensive public research university in the Dayton, Ohio region, offering undergraduate, graduate, and professional programs including a medical school. Situated next to Wright‑Patterson Air Force Base, the university engages with the Air Force Research Laboratory and regional defense partners through an applied research institute experienced in government and industry contracts. A community‑based medical school with multiple affiliated teaching hospitals provides clinical access for translational studies and regional workforce pipelines. Research is supported by competitive federal sponsors, with recent awards from NSF, NIH, and the Department of Defense. A dedicated technology transfer office assists with IP protection, licensing, and startup formation.

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