Next-generation sequencing and genomic services
NUSeq is the only Northwestern University-wide Facility dedicated to providing infrastructure and expertise on state-of-the-art genome sequencing capabilities and other genomics technologies. Besides wet lab operations, bioinformatics and data mining are also an integral component of the NUSeq service line.
Major technologies available at NUSeq include next-generation sequencing (NGS), microarray, droplet digital PCR (ddPCR), real-time quantitative PCR, for whole genome/exome/gene panel sequencing, transcriptomics (bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics), global and targeted genotyping, epigenetic/epigenomic changes (both methylation sequencing and methylation EPIC array analysis), DNA-protein interaction, 3D genome and DNA accessibility, and metagenomics. For spatial transcriptomics, the Core is equipped with 10x Genomics Visium/Visium HD, Xenium, and Atera. Major sequencers include Illumina NovaSeq X Plus, MiSeq i100, Element AVITI, Oxford Nanopore, and PacBio Revio.
About Northwestern University
Northwestern University is a comprehensive private research university with campuses in Evanston and downtown Chicago and a collaborative, cross‑disciplinary culture. Integration with a major hospital system enables clinical research, diverse patient access, and rapid translation from bench to bedside. Shared research cores, prototyping facilities, a campus incubator, and dedicated corporate engagement teams make it straightforward to scope projects, structure agreements, and place talent. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, and DoD, complemented by foundation and industry partnerships. A dedicated technology transfer office advances IP strategy, licensing, and startup formation.
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