Prebiotic-based chewing gum for enhanced oral health
A prebiotic chewing gum containing L-arginine, sodium bicarbonate, and hydroxyapatite to promote beneficial oral bacteria, reduce pathogens, and improve oral hygiene, especially for orthodontic patients, children, and individuals with special needs.
Overview
This innovative chewing gum formulation is designed to enhance oral health through the use of prebiotic ingredients, including L-arginine, sodium bicarbonate, and hydroxyapatite. It targets the selective promotion of beneficial oral bacteria while reducing pathogenic species, providing a convenient and effective method for maintaining oral hygiene. This product is particularly beneficial for orthodontic patients, children, adults who struggle with traditional oral care routines, and special needs dental patients.
Technical specifications
The chewing gum features a unique blend of ingredients that work synergistically to improve oral health:
- L-arginine: Promotes the growth of beneficial bacteria and inhibits pathogens.
- Sodium bicarbonate: Neutralizes acids in the mouth, reducing the risk of cavities.
- Hydroxyapatite: Supports enamel remineralization and reduces sensitivity.
The gum is designed for easy use throughout the day, offering a practical alternative to traditional oral hygiene methods like brushing and flossing. It is currently in the prototype development stage, with a focus on optimizing texture, stability, and controlled ingredient release.
Technology readiness level
The technology is at TRL 4, having completed initial formulation and secured a provisional patent. The next steps include developing a functional prototype and conducting pilot studies to evaluate its effects on oral microbiome balance, plaque reduction, and enamel remineralization. These studies will involve microbiological analyses, pH monitoring, and user feedback to refine the product further.
About University of Connecticut
UConn is a comprehensive public research university and the state’s flagship, with its main campus in Storrs and an academic medical center in Farmington. Industry engages through UConn Tech Park—anchored by the Innovation Partnership Building—with shared labs, pilot‑scale testbeds, and advanced prototyping for collaborators. Integration with UConn Health enables clinical collaborations and translation, while Hartford and Stamford campuses connect companies to talent along the New York–Boston corridor; a statewide extension network supports technology adoption. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, USDA, and DOD. A dedicated technology commercialization office and the Technology Incubation Program support IP, licensing, and startup incubation across multiple sites.
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