Rnai-based bioinsecticide for nilaparvata lugens control in rice
Innovative RNAi-based bioinsecticide targets Nilaparvata lugens, reducing herbivory in rice crops with high specificity and minimal environmental impact. Proven platform projects pest lethality within 10 days post-application, aiming for field-scale testing soon.
Overview
HMS Agroscience presents an RNAi-based bioinsecticide targeting Nilaparvata lugens, a significant pest in rice cultivation. This solution utilizes RNA interference (RNAi) to silence specific genes critical to the pest's survival, effectively reducing herbivory and protecting crops. The bioinsecticide offers high target specificity and a favorable environmental profile, leveraging a spray-applied formulation that minimizes non-target impacts. By harnessing our proven platform, which has shown success against other pests, we anticipate rapid efficacy and target specificity validation for N. lugens.
Technical specifications
- RNAi Mechanism: Utilizes double-stranded RNA (dsRNA) to silence essential genes in N. lugens, reducing its population.
- Application Method: Spray-applied formulation designed to deliver dsRNA effectively, ensuring stability and protection from degradation.
- Efficacy: Prior success includes 100% mortality in Diabrotica speciosa and a patent application for Euschistus heros target genes.
- Integrated Pest Management: Potential to enhance chemical insecticide effectiveness by targeting resistance mechanisms.
Technology readiness level
The N. lugens-specific RNAi bioinsecticide is at TRL 3. Initial laboratory assays have been conducted, with plans for greenhouse experiments and eventual field trials. The technology is advancing towards TRLs 7-9, benefiting from our ongoing RNAi-based bioinsecticide developments.
About HMS Agroscience
HMS Agroscience is a technical-scientific consultancy firm specializing in biotechnological innovations for the agribusiness sector. With over two decades of expertise, the company utilizes advanced molecular tools, including gene silencing and gene editing, to provide sustainable solutions for challenges in agriculture, livestock, the food sector, and industry. Their core offerings include the management of Research, Development, and Innovation (PDI) projects, specialized technical consulting, training for research and sales teams, and the implementation of in-house innovation departments. Additionally, the firm facilitates tech-scouting and business-bridging, acting as a connector between startups, private companies, universities, and public institutions to foster collaborative research and development.
By leveraging their multidisciplinary team, HMS Agroscience supports partners in navigating the complexities of technological development, from project structuring and funding applications to managing intellectual property and technical execution. The company is a recognized Unicamp-affiliated venture, dedicated to transforming scientific knowledge into practical tools that enhance productivity and sustainability in the field. Their services are designed to help companies of all sizes address specific agricultural limitations, offering customized strategies that ensure efficiency, compliance with innovation laws, and the effective delivery of innovative technological solutions.
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