Lc-ms-based mycotoxin identification and quantification method
A novel LC-MS-based method for the identification and quantification of mycotoxins, offering customization for HPLC and immunological methods, enabling broad application in various biological samples.
Overview
This innovative solution leverages liquid chromatography-mass spectrometry (LC-MS) to identify and quantify mycotoxins in various biological samples. Developed by Clarkson University, the method can be customized to work with high-performance liquid chromatography (HPLC) and immunological methods, which could potentially reduce costs and simplify the process for users without mass spectrometry expertise. This adaptability makes it valuable for applications in food safety, agriculture, and healthcare.
Technical specifications
Key features:
- Utilizes LC-MS for precise detection and quantification of mycotoxins.
- Potential customization for HPLC and immunological methods for broader accessibility.
- Applicable to a wide range of samples including tissues, cell cultures, and biological fluids.
- Development includes optimizing sample preparation methods such as centrifugation and filtration.
- The method is patentable, providing a pathway to commercialization.
Technology readiness level
This method is currently at Technology Readiness Level 4, indicating that it has been validated in a laboratory environment. The next steps include further tests and optimizations to refine the sample preparation process and validate the quantification capabilities in practical scenarios. The expected timeline for development and validation is 10-14 months.
About Clarkson University
Clarkson University is a private, national research university with a STEM-oriented character and a multi-campus footprint anchored in Potsdam, New York. Companies engage through a state-designated Center for Advanced Technology in advanced materials that supports industry collaboration and access to applied expertise. A Capital Region campus and a Hudson Valley research site extend reach into New York’s technology and manufacturing corridors, while co-op and internship pathways align talent with corporate R&D needs. Research is backed by competitive federal funding from major U.S. agencies such as the National Science Foundation and National Institutes of Health. A dedicated technology transfer office and the Shipley Center for Innovation provide IP support, incubation, and startup acceleration.
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