3 other scientists and I founded BioGrammatics in 2008 to support protein expression with the yeast, Pichia pastoris (re-classified Komagataella phaffii). We helped develop Pichia as a host for recombinant protein expression in the 80's, and have now used Pichia for the production of 100's of proteins including drugs (insulin analogs, HIV inhibitors, Antibodies, vaccines), food/feed & flavor proteins (Impossible Foods heme protein, The EVERY EGG, Phytase, Avaia protein powder), even Bio Toys (e.g. a fluorescent squirt gun). Pichia has become the most powerful and successful eukaryotic microbe for protein production. Having assembled one of the first Pichia genomes in 2008, we are now excited to use AI with "omic" data and the power of yeast genetics to further improve protein production.