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Free in vivo testing: Unleash your molecule's potential as a crop protector
- Background
- What we're looking for
- What we can offer you
- Who we are
- Q&A
Have questions about this request?
Get them answered by the team at BASF.
Background
You’ve already done all the hard work of synthesizing your molecule. Maybe it wasn’t the blockbuster pharmaceutical you envisioned, but it still has potential!
Now, we would like to partner to bring new life and impact from your chemistry. You may submit multiple compounds, and we will screen them using our computer models. If they are selected, you will receive the biological results for each compound as a potential herbicide, fungicide and insecticide, and you are free to publish the results.
If there is a hit, it’s up to you to decide about follow up collaboration.
Start the collaboration with us: let’s discover together if that next crop protection blockbuster is sitting in your deep freezer!
Process
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Submit proposal on Halo
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Sign MTA agreement through DocuSign
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Upload file with structures to BASF's platform
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In silico evaluation & BASF decision
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In vivo test of selected compound at BASF
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Return of in vivo results for publication
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Further collaboration
What we're looking for
We are looking for novel compounds, such as organic molecules, natural products, and fragment-like molecules, which could be subjected to screening within our research facility, with the goal of developing new crop protection products.
Solutions of interest include:
- Small organic molecules
- Natural products
- Virtual compounds (if deliverable as physical sample by partner after positive in silico testing by BASF)
- Single chemical compounds (in a dry form)
Our must-have requirements are:
- The minimum amount of compound we will accept is 5 mg (the standard amount is 8 mg).
- The material shall have purity greater than 80% as determined by current state-of-the-art analysis.
Our nice-to-have's are:
- Additional amounts of compound available for further screenings (20-100 mg) if needed.
- Analogues compounds of submitted molecule if the parent compound turns out to be a hit in the initial screening.
What's out of scope:
- Extracts or mixtures of compounds
- Solutions in solvents
- Metal-containing molecules
- Polymers
- Nanoparticles
- Microorganisms
- Toxic or explosive compounds
What we can offer you
Benefits:
Data
Biological results from the preliminary tests and results from philanthropic public health programs against human pathogens (e.g. malaria)-if selected by BASF and priori agreed with partner to test.Expertise
Partner receive logistic support and guidance over each step of the collaboration. Possibility to develop further collaboration with BASF researchers, based on preliminary results.Facilities and Services
Free shipping of participant's compounds to BASF. To ensure the best solution and simple procedures, we also provide you free of charge our packaging materials (vials/tubes and boxes).Compounds and Reagents
Synthesis cost for the re-ordered compound for further in vivo tests could be reimbursed.Who we are
As a global chemical company, we operate in diverse markets with varying requirements. To ensure responsible conduct and maintain our license to operate, we are guided by our core values and standards. These values shape our daily actions and foster respectful relationships with colleagues, customers, and partners.
Our teams are committed to putting health and safety first, making sustainability a part of every decision, and meeting strict compliance and environmental standards. We embrace diversity—in people, perspectives, and experiences—and promote open feedback grounded in honesty, respect, and trust. We see setbacks as opportunities to learn and improve.
Learn moreReviewers
AP
Anna aleksandra Michrowska Pianowska
Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition
Emir Islamovic
Innovation and Partnership Manager
LJ
Lauren Junker
Technology Scout
TH
Tom Holcombe
Collaboration & Scouting NA
KB
Kavita Bitra
Technology scout
MF
Megan Franklin
Innovation Scout
SS
Sophia Steffens
Innovation & Scouting
Q&A with BASF
The Q&A is now closed.
Sort by:
Most upvoted
Q.
Can you provide more specifics about the types of assays that would be performed?
2
A.
hi Kenzo,
Your compounds will be assessed by preliminary in vivo screening as potential herbicides, fungicides and insecticides. We test on 3-5 species from each indication. For more information please contact me at: oipAgro@basf.com
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 18, 2024
Is this response helpful?
0
0
Q.
For the in vivo test, will I have to pay for the molecule shipment?
1
A.
no, we cover the shipping costs and send you our vials and packing materials.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 8, 2024
Is this response helpful?
1
0
A.
let me get this straight, If my proposal is accepted, the BASF will send me the material for me make the tests?
Or the BASF will make all of the tests and send me the results?
Thank you!
All the best,
Carol
1
A.
Dear Carol,
we send you our empty vials and box so you can ship your compounds to us. We test them at our side in Limburgerhof and you get back the biological results:)
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 15, 2024
Is this response helpful?
1
0
A.
Ok, I got it. I don't have the compounds, only the 3D molecules of interest. There are some way to participate without buy the molecules?
1
A.
Dear Caroline,
In this case it will not be possible to participate in the program. We are not going to synthesize your compounds at such early stage of the project.
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 16, 2024
Is this response helpful?
1
0
Q.
Will this be a recuring call or a one time opportunity? We have a library of novel bacteria we are starting to screen for molecules of interest but are just in the preliminary stages.
April 22, 2024
1
A.
Dear Danielle,
We are planning to repeat our challenge:) You can also contact my Team at <oipAgro@basf.com> anytime you are ready to start the collaboration. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 24, 2024
Is this response helpful?
0
0
Q.
Would a functionalized carbon-based material be within scope? Our material is fabricated from graphite with flake sizes on the order of microns. The compound is a dry powder with fungicidal & fertilizer properties.
1
A.
thank you for your interest and question, but I am afraid your compound is not suitable for the current program.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
May 13, 2024
Is this response helpful?
0
0
Q.
Hello, all the compounds must be new or do you also accept compounds already reported by others?
1
Q.
Would they be interested in screening a perlite ai with designated IRAC MoA UNM (pending registration)? It can be used as a stand-alone ai or formated dual MoA WP or WG.
DS
May 16, 2024
1
A.
Dear David,
Unfortunately, we are not interested in perlite.
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
May 17, 2024
Is this response helpful?
0
0
Q.
Are species-specific, RNAi bioactives of interest?
1
A.
Dear Erin,
Unfortunately RNAi bioactives are out of scope for this program. Maybe you find other our challenges interesting:
https://www.basf.com/global/en/who-we-are/innovation/Innovate_with_us.html#%7B%220%22%3A%5B%5B%22q%22%2C%5B%22collaboration%22%5D%5D%5D%7D.
Our department of our company will get in touch wit you. Please write to : SANDRA TAKAKI SCHMIDT <sandra.takaki@basf.com>.
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
May 17, 2024
Is this response helpful?
0
0
Q.
Would you consider testing commercially available volatiles that induce anosmia to mosquitoes and other insect pests?
1
A.
Dear Kostas,
Unfortunately, no interest from our side in testing such compounds.
best wishes,
Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
May 17, 2024
Is this response helpful?
0
0
Q.
Have BASF considered non-volatile hop-derived compounds previously? They are fascinating, whether from as ionophores, bittering agents and active against many Gram-positive bacteria.
1
A.
Humulone and Lupulone have been tested in all indications, but no significant activity was seen. I do not know about other hops ingredients. The antibiotic activity is supposed to be based on membrane activity, which would not be very interesting for us.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
April 8, 2024
Is this response helpful?
0
0
Q.
1. How many samples are possible to send? I want to know the maximum number of samples allowed.
2. If a proposal is submitted up to May 31st , then vials and packing materials for samples will be sent?
1
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