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Seed treatment technologies for Pythium control
  • Background
  • What we're looking for
  • What we can offer you
  • Who we are
  • Q&A
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Background

Pythium is a soil-borne oomycete (water mold) that infects seeds and young seedlings, causing damping-off and early root rot across a wide range of European crops. Its ability to thrive in cool, wet conditions makes early-season infections particularly damaging, often resulting in poor germination, uneven emergence, weakened early plant development, and reduced yield potential. 

 

Growers have traditionally relied on chemical seed treatments to limit Pythium infection during the establishment phase. However, many of the active ingredients effective against oomycetes have recently been banned or restricted in the EU due to evolving safety and environmental regulations. As a result, farmers have limited effective options, leaving crops more vulnerable during critical early growth stages. 

 

There is a growing need for new, effective seed-treatment solutions that provide reliable Pythium control while complying with EU regulations. Bio-based approaches or chemical treatments with low-risk profiles could restore early-season protection, strengthen crop establishment, and offer growers a sustainable and regulation-compliant path forward.

What we're looking for

We are looking for seed-treatment technologies with the potential to control Pythium under European soil and climate conditions and that can ultimately be developed into EU-compliant, low-risk or biological products suitable for use on corn.

Solutions of interest include:
  • Microbial biocontrol agents (live organisms)
  • Bio-derived fungicidal compounds
  • Plant extracts
  • Novel chemical fungicides
Our must-have requirements are:
  • Preliminary data demonstrating efficacy against Pythium
  • Seed-safe on corn (should not lead to a decrease in germination rate)
  • Potential to be applied at low volumes consistent with seed-treatment coating limits
  • Plausible pathway toward EU regulatory acceptance for plant protection use
Our nice-to-have's are:
  • Shelf life of at least 24 months
  • Compatible with seed treatment formulations and application methods
What's out of scope:
  • Chemistries banned or restricted under EU regulations
  • Use of microplastics in formulations or delivery systems
Acceptable technology readiness levels (TRL):
Levels 2-9
What we can offer you
Eligible partnership models:
Co-developmentSupply/purchaseLicensingFee-for-serviceEquity investmentFellowships/Postdocs
Benefits:
Compensation
Financial support will be evaluated on a proposal-by-proposal basis. Selected proposals may be eligible for funding starting in 2026, typically ranging from $50,000–$200,000 USD, depending on project scope and stage. Innovators may also license their active ingredient, formulation, or microbial strain to the company for use in seed treatment.
Expertise
Successful applicants will work with experts from UPL’s Seed Applied Technologies division to manage the project.
Tools and Technologies
Our organization offers extensive analytical capabilities that may be made available to support the selected proposal. Relevant technologies include in vitro/in vivo efficacy evaluation, active ingredient quantitation, and mode of action assays. Access to these tools will be considered based on project scope and specific needs.
Data
Access to relevant proprietary data to support solution development and alignment.
Facilities and Services
Successful applicants will have access to UPLs global network of research stations and greenhouse/lab facilities to conduct research year-round.
Market Access
UPL has market access to the main agricultural countries. Any technology developed can certainly be introduced and commercialized in these countries, according to usage needs and in compliance with current regulations.
Who we are

At UPL we are on a mission to Reimagine Sustainability for farmers and food systems – feeding the world while nurturing the planet. Each and every member of our team is making a difference – to our company’s growth, to our industry’s success, and to our sustainable food future. Our employees and teams reflect the diversity of our customers, the regions in which we operate, and the societies we serve.

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Reviewers
Q&A with UPL

The Q&A is now closed.

Sort by:
Q.
Would you be interested in a technology, with a physical approach, to replace chemical seed-treatment of any type?
5
A.
Dear Michelle, thanks for the great question. We are currently evaluating all proposals, so feel free to submit a proposal. Best, Constanze
CH
Constanze Holzfuß, Portfolio Manager, UPL
December 12, 2025
Is this response helpful?
0
0
Q.
Are biostimulants of interest? What about solutions which have general antifungal properties through ISR but have not been tested on Pythium?
1
A.
Dear Henry, thanks for the great question! We are currently focusing on biocontrol solutions. There should be some evidence that the solution is working as Pythium control agent. Best, Constanze
CH
Constanze Holzfuß, Portfolio Manager, UPL
January 16, 2026
Is this response helpful?
0
0
Q.
The institution where I work holds the NCMA, which has a large collection of microalgae, and we are now exploring applications for 400 species/strains. Would you be interested in testing activities against Phythium?
1
Q.
We have a food grade formulation proven to be effective for inactivating fungal pathogens for produce. We haven’t tested for pythium. Would this be of interest for your application?
1
Q.
Are you interested in a microbial wild-type strain producing high levels of DAPG (natural compound with activity against Pythium)? This would give you both options: develop a biocontrol agent and/or anti-fungal compound.
1
A.
Dear Dietmar, thanks for the great question. We are currently evaluating all proposals, so feel free to submit a proposal. Best, Constanze
CH
Constanze Holzfuß, Portfolio Manager, UPL
January 16, 2026
Is this response helpful?
0
0
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